| Condition | Description | Symptoms | Diagnosis | Treatment | 
                  
                    | Acanthosis
                      nigricans | Inherited form seen in
                      Dachshunds; secondary form caused by friction, hormonal
                      abnormalities, or hypersensitivities | Darkening of the skin; in
                      secondary form see scratching and hair loss | History, physical exam; in
                      secondary form, testing to determine underlying cause | Primary: no treatment;
                      secondary: treat underlying disease; in some cases,
                      steroids and Vitamin E supplementation | 
                  
                    | Acral
                      lick dermatitis (neurodermatitis) | Self-licking in dogs results in self-trauma; possible
                      causes include anxiety, boredom, stress (e.g., new member
                      in household); licking can develop into an obsessive
                      behavior | Red, hairless, well-circumscribed, sometimes raised
                      lesion usually on the leg; if chronic, will drain | Exclude other causes; history important | Relieve underlying cause e.g., anxiety; restrict
                      licking, e.g., elizabethan
                      collar; behavior modifying medication may be
                      necessary | 
                  
                    | Adrenal sex hormone
                      responsive dermatosis | More common in Pomeranians,
                      Chows, Keeshonden, and Samoyeds | Hair loss starts on neck,
                      tail, back of thighs, and progresses to trunk; dog appears
                      to have a 'puppy coat'; skin darkens | Biopsy; eliminate other
                      causes | Mitotane is optional | 
                  
                    | Allergic
                      and irritant contact dermatitis | An allergic reaction following exposure to antibiotics
                      applied to the skin; metals such as nickel; materials such
                      as rubber, wool, and plastic; and chemicals such as dyes
                      and carpet deodorizers; or inflammation caused by
                      irritating substances such as poison ivy. Generally
                      requires multiple exposures. | Red skin and small bumps or blisters on the areas of
                      skin that are sparsely haired and directly exposed to the
                      offending substance, itching; hair loss in chronic
                      conditions | Patch test, exclusion trials | Restrict exposure to the allergen or contact irritant
                      in the dog's environment; steroids, antihistamines | 
                  
                    | Alopecia areata 
 (also Flank Alopecia)
 | Thought to be an autoimmune
                      disorder | Patches of hair loss
                      especially on head, neck, and body; no itching | Microscopic examination of
                      hairs; biopsy | Usually recover
                      spontaneously | 
                  
                    | Atopy
                      
                      (allergic inhalant dermatitis) | Allergic reaction to something the dog inhales such as
                      pollen, house dust mites, and mold | Licking of feet, inflamed ears, itching, redness, and
                      hair loss; sometimes development of infection or hot spots | Intradermal
                      or serologic (blood) testing for allergies | Reduce exposure to allergen (what the dog is allergic
                      to); steroids, fatty
                      acid supplements, biotin,
                      antihistamines, shampoos, immunotherapy | 
                  
                    | Bacterial infection (pyoderma)
                       See Folliculitis | Often occurs as a result of another condition such as a
                      parasitic, allergic, or hormonal condition |  |  |  | 
                  
                    | Black
                      hair follicular dysplasia/alopecia/dystrophy | Rare hereditary disease in
                      dogs with hair of multiple colors; more common in Bearded
                      Collies, Basset Hounds, Salukis, Beagles, Dachshunds, and
                      Pointers | Loss of dark or black hair
                      only; symptoms appear between 3 and 6 weeks of age;
                      sometimes scaling | Clinical signs, biopsy | Shampoos for scaling if
                      necessary | 
                  
                    | Callus | Results from chronic
                      pressure, especially in large breed dogs | Thickened, hairless raised
                      areas over bony pressure points such as elbows; may become
                      secondarily infected | History, clinical signs | Provide softer bedding and
                      padding around affected area | 
                  
                    | Castration responsive
                      dermatosis | More common in young
                      unneutered dogs, and in Chows, Samoyeds, Keeshonden,
                      Alaskan Malamutes, Miniature Poodles, and Pomeranians | Symmetrical hair loss in
                      genital area and neck; hair loss may progress onto trunk;
                      skin may appear darker; severe scaling; hair color may
                      fade; coat is similar to a 'puppy coat' | Physical exam and history;
                      eliminate other causes; blood tests for hormone
                      levels | Castration | 
                  
                    | Chemotherapy | Loss of hair due to chemotherapy
                      is a concern for dog owners | Dogs with continuously
                      growing hair, e.g., Poodles and Maltese, often lose some
                      hair; dogs may lose whiskers | History | None, hair will regrow after
                      chemotherapy discontinued; may regrow in a different color
                      or texture | 
                  
                    | Cheyletiella
                      
                      (rabbit fur mite) mange | Infection with the Cheyletiella mite | Itching, scaliness;
                      some hair loss, if severe | Skin scraping and microscopic examination - the mite is
                      often very difficult to find | Pyrethrin,
                      Permethrin
                      (Do NOT use permethrin on cats.) | 
                  
                    | Color
                      dilution/mutant alopecia | Hereditary condition
                      affecting dogs with blue (diluted black) or fawn coat
                      colors; more common in Dobermans, Dachshunds, Great Danes,
                      Yorkshire Terriers, Whippets, and Greyhounds | Hair in the blue- and fawn-colored
                      areas starts to thin at around 6 months of age; secondary
                      folliculitis often develops | Breed; history; and coat
                      color | None; avoid excessive
                      grooming or harsh shampoos; protect skin to prevent
                      secondary bacterial infections | 
                  
                    | Congenital hypotrichosis | Congenital lack of hair | Puppies born with little or
                      no hair; any hair they are born with is lost by 4 months
                      of age | Physical exam; biopsy | None | 
                  
                    | Cushing's
                      disease (hyperadrenocorticism) | Caused by an increase in
                      corticosteroids in the body - either due to increased
                      production by the body or as a side effect of high doses
                      or prolonged therapy with corticosteroids | Hair loss, thinning of skin,
                      hyperpigmentation,
                      easy bruising, seborrhea, comedones (black heads), may see
                      calcinosis cutis; lethargy, increased thirst and
                      urination, potbellied appearance | Adrenal gland function
                      tests, urinalysis, chemistry panel, CBC | If due to glandular tumors,
                      selegiline, o,p-DDD (Mitotane), or surgical removal of
                      tumor; if due to high steroid doses, withdraw use of
                      steroids slowly | 
                  
                    | Cyclic (cicatrical)
                      alopecia; seasonal flank alopecia | Growth cycle of hair stops
                      at certain times of the year | Symmetrical hair loss with
                      definite borders; usually on back and flanks; skin may
                      become darker | History, clinical signs,
                      biopsy | None | 
                  
                    | Demodectic
                      mange(red mange, puppy mange)
 | Infection with the Demodex mite - occurs when
                      the immune system is deficient | Hair loss, scaliness,
                      redness, pustules,
                      ulcers,
                      sometimes itching, darkening of the skin | Skin scraping and microscopic examination | NO Steroids! Amitraz (Mitaban) dips | 
                  
                    | Dermatomyositis | Some breeds predisposed;
                      cause unknown; aggravated by trauma and UV light | Redness, scaling, crusting,
                      hair loss, and scarring on face, ears, and tail; atrophy
                      of muscles involved in chewing | Skin biopsy | Minimize trauma and exposure
                      to UV light; Vitamin E, fatty acids, short term use of
                      prednisone, oxpentoxifylline; some severe cases do not
                      respond to treatment, and euthanasia may be considered | 
                  
                    | Diabetes mellitus | Abnormal immunity makes
                      diabetic dogs susceptible to infection and other skin
                      conditions | Thin skin; some hair loss;
                      seborrhea; recurrent bacterial infections; unregulated
                      dogs also have many other signs of disease; may develop
                      epidermal metabolic necrosis
                      or xanthoma | Blood testing | Dietary changes; insulin | 
                  
                    | Drug or injection reaction | Rare skin reaction to a drug
                      which is inhaled, given orally, or applied topically;
                      more common with penicillins, sulfonamides, and
                      cephalosporins; usually occurs within 2 weeks of giving
                      the drug | Can vary widely and may
                      include itching, hair loss, redness, swelling, papules,
                      crusts,
                      ulcers,
                      and draining wounds | History of being treated
                      with a drug, symptoms, biopsy | Discontinue offending drug;
                      treat symptomatically | 
                  
                    | Epidermal metabolic necrosis
                      (necrolytic migratory erythema, hepatocutaneous disease) | Uncommon skin disease in
                      older dogs; skin lesions develop in dogs with certain
                      diseases including liver disease, diabetes mellitus, and
                      some pancreatic tumors | Reddened, often ulcerated
                      areas with hair loss and crusts;
                      foot pads may be thickened | Biopsy; look for underlying
                      disease | Treat underlying disease;
                      supportive therapy; poor prognosis | 
                  
                    | Erythema multiforme | Hypersensitivity reaction to
                      infections or drugs; may also be caused by cancer
                      or other diseases | Hair loss, 'bull's-eye'
                      lesions, and vesicles
                      often around mouth, ears, groin, and axilla;
                      in some instances, ulcers
                      develop; depression, fever | History, clinical signs,
                      rule out other diseases causing similar signs; skin biopsy | Treat or remove underlying
                      cause | 
                  
                    | Estrogen responsive
                      dermatosis (ovarian imbalance type II) | More common in young spayed
                      dogs, and in Dachshunds and Boxers | Hair loss starting at the
                      genital area and flanks and moving forward; hair color may
                      fade; coat is similar to a 'puppy coat' | Physical exam and history;
                      eliminate other causes; response to therapy | Estrogen replacement
                      therapy; caution - can have severe side effects | 
                  
                    | Flea
                      allergy dermatitis (flea bite hypersensitivity) | Severe reaction by the animal to the saliva of the flea | Intense itching, redness, hair loss papules,
                      crusts,
                      and scales;
                      sometimes development of infection or hot spots | Presence of fleas; reaction to intradermal
                      testing | Flea
                      control in the environment and on the dog; steroids
                      and antihistamines for the itching | 
                  
                    | Follicular
                      dystrophy/alopecia/dysplasia (abnormal development or
                      growth of hair) See Congenital hypotrichosis, Color dilution/mutant
                      alopecia, Black hair folliclular dystrophy/alopecia,
                      Follicular dysplasia (non-color linked) | May be congenital (certain
                      breeds are at increased risk) or acquired later in life
                      from infections, hormonal abnormalities, cancer
                      drugs, and some other diseases | Hair loss, sometimes only
                      hair of a certain color; sometimes scaling | Clinical signs, breed, skin
                      biopsy | In congenital disease,
                      treatment of secondary problems such as infections or
                      scaling; in acquired disease treat underlying cause | 
                  
                    | Follicular
                      dystrophy/dysplasia (non-color linked) | Patchy hair loss of unknown
                      cause seen in the Siberian Husky, Doberman Pinscher,
                      Airedale, Boxer, Staffordshire Bull Terrier, Curly Coated
                      Retriever, Irish Water Spaniel, and Portuguese Water Dog | In Huskies, hair loss on the
                      body, reddish tinge to hair; in Dobermans, hair loss over
                      lumbar area; in Boxers and Terriers, hair loss over lumbar
                      area, skin may be hyperpigmented;
                      in the Retrievers and Spaniels, loss of guard hairs on
                      back and trunk and secondary hairs are dull and lighter in
                      color | Breed, biopsy | None | 
                  
                    | Folliculitis | Infection of the hair follicles,
                      often with staph bacteria; symptoms usually appear on skin
                      with less hair, such as the abdomen | Pustules
                      form in follicles and break open to form 'bull's-eye,'
                      'annular,' and 'target lesions,' which have crusty
                      centers and red or darkening on the periphery, and
                      'epidermal collarettes,' which appear as rings of scaly
                      skin; may itch; short-coated breeds may develop small
                      tufts of hair, which are lost; breeds with long coats may
                      have seborrhea | Skin scraping; culture;
                      biopsy | Antibiotics for at least 4
                      weeks - continue antibiotics 10 days beyond the apparent
                      cure; if recurs, look for underlying problem such as
                      allergy or hormonal imbalance | 
                  
                    | Food
                      allergies | Allergic reaction to something in the diet | Licking of feet, inflamed ears, itching, redness, and
                      hair loss; sometimes development of infection or hot spots | Food elimination trials | Change in diet | 
                  
                    | Granulomas | May be due to infections;
                      the body's reaction to foreign material such as plant
                      material (e.g., foxtail) and suture material; other
                      constant irritation; or unknown causes | Solid firm nodules
                      of varying sizes; those due to foreign bodies often have
                      draining tracts; may develop hair loss, ulcers,
                      and secondary
                      infections | History, clinical signs,
                      biopsy, surgical exploratory | Surgical removal of the
                      foreign body (in the case of plant material, tracts may be
                      extensive and require major surgery); antibiotics if
                      infected; treat any other underlying cause | 
                  
                    | Growth hormone responsive
                      alopecia | Not well understood; thought
                      to be caused by an enzyme deficiency or decrease of
                      adrenal 
                      hormones, which allows certain other hormones to
                      accumulate in the body: more common in Pomeranians, Chow
                      Chows, Keeshonden, Samoyeds, and Poodles | Hair loss on neck, tail, and
                      the back of the thighs; skin darkens; usually starts when
                      dog is less than two years old | Hormonal blood testing | Neuter animal; growth
                      hormone; hormonal supplementation | 
                  
                    | Growth Hormone Treatment: Growth hormone (somatotropin) is a polypeptide produced by the anterior pituitary that acts either directly on target tissues or indirectly through insulin-like growth factors (somatomedins) produced by the liver. It is necessary for hair growth and for development of elastin fibers in the skin. It is used to treat growth hormone-responsive alopecia in dogs. Either bovine, porcine, or human growth hormone (0.1 IU/kg, 3 times/wk for 4-6 wk) is effective. Hair usually regrows in 2-3 mo, and remission may last from 6 mo to 3 yr. Growth hormone is diabetogenic, and dogs can develop transient or permanent diabetes mellitus during therapy. Weekly monitoring of blood glucose before and during therapy is recommended.
   | 
                  
                    | Hair loss during pregnancy
                      and nursing  ('blowing her coat,' telogen
                      effluvium) | Excess shedding that can
                      also occur in other stressful circumstances such as
                      illness or surgery | Sudden and widespread hair
                      loss | History, clinical signs | Treat any underlying
                      condition; hair will grow back | 
                  
                    | Histiocytosis | There are several kinds of
                      histiocytosis: malignant,
                      which is a cancer
                      that affects the skin and internal organs; systemic, which
                      is a rare disease which affects skin and internal organs;
                      and cutaneous,
                      which is a benign
                      disease affecting the skin | All cause nodules
                      with hair loss; malignant and systemic also have ulcers | Biopsy, fine
                      needle aspirate; | Malignant: none effective,
                      may need to consider euthanasia; systemic: poor response
                      to chemotherapy; cutaneous: corticosteroids, relapse is
                      common, especially in Shar-Peis | 
                  
                    | Hyperestrogenism  (ovarian
                      imbalance type I) | Rare disease in which female
                      animals have excess levels of estrogen; can be caused by cancer
                      of the ovaries | Symmetrical loss of hair;
                      hair pulls out easily; darkening of the skin; enlarged
                      nipples and vulva; may rarely see seborrhea and itching | History, physical exam, rule
                      out other causes of hair loss, measure blood estrogen
                      levels | Spay; look for metastasis
                      to the lungs | 
                  
                    | Hypothyroidism | Decreased production of
                      thyroid hormone;
                      most common hormonal disease affecting the skin in dogs | Hair loss, dry and brittle
                      hair, seborrhea; secondary bacterial and yeast infections;
                      lethargy, obesity, slow heart rate; changes in skin
                      pigmentation may occur | Thyroid gland function
                      tests, chemistry panel, CBC | Lifetime thyroid
                      supplementation | 
                  
                    | Injection site alopecia | Hair loss at the site of an
                      injection of a medication or vaccine; skin may become
                      thickened; in cats, ulcers
                      may develop | Hair loss occurs several
                      months after injection; area may become hyperpigmented | History and physical
                      examination | None; the condition is
                      permanent | 
                  
                    | Interstitial cell tumor | Tumor
                      of the testicle; may not cause any skin changes | If skin changes occur, see
                      seborrhea, loss of hair on the trunk, enlargement of the
                      tail gland and perianal glands; may see increased pigment
                      in the skin | Biopsy | Castration; anti-seborrheic
                      shampoos | 
                  
                    | Kerion | Complication of ringworm
                      infection | Nodule
                      with hair loss and multiple draining tracts; may not see
                      other signs of ringworm | Culture, biopsy | Clip area and apply topical
                      treatment and shampoos; may require systemic treatment
                      with ketoconazole or itraconazole | 
                  
                    | Leishmaniasis | Caused by a parasite of
                      blood cells; can be transmitted to people who develop a
                      very severe disease | Hair loss, scaling, ulcers
                      on nose and ears, sometimes nodules;
                      many other nonskin-related signs | Identify the organism in
                      blood or biopsy; blood tests | Because it causes severe
                      disease in people, and treatment of dogs is not curative,
                      euthanasia may be performed | 
                  
                    | Lice | Infection with several species of lice | Variable; itching, hair loss, crusts,
                      rough hair coat | Finding lice or nits on skin or hair | Pyrethrin,
                      ivermectin (off-label use*), Permethrin
                      (Do NOT use permethrin on cats.) | 
                  
                    | Malassezia | Usually follows some other underlying disease | Itching, redness, hair loss, greasy scales;
                      if chronic, develop hyperpigmentation | Skin scraping/smear and microscopic examination,
                      culture | Treat underlying disease; oral ketoconazole; miconazole
                      shampoos | 
                  
                    | Nasal solar dermatitis
                       See solar dermatitis | See solar dermatitis |  |  |  | 
                  
                    | Pattern alopecia (pattern
                      baldness) | Three types; hair loss may
                      occur on the ears of Dachshunds (pinnal alopecia); neck,
                      thighs, and tail of American Water Spaniels and Portuguese
                      Water Dogs; abdomen and the back of the thighs of
                      Dachshunds, Chihuahuas, Whippets, and Greyhounds | Hair loss in described areas | Breed, history, biopsy | None | 
                  
                    | Pelodera dermatitis | Accidental infection with larvae from a non-parasitic
                      worm that lives in straw and other organic material | Affects areas of skin touching ground; intense itching,
                      redness, hair loss, papules,
                      crusts,
                      and 
                      scales | Skin scraping and microscopic examination | Remove bedding; mild antibacterial shampoo; steroids if
                      necessary to control itching | 
                  
                    | Pituitary
                      dwarfism | Hereditary condition in
                      which the pituitary gland does not produce the necessary hormones | Young puppies fail to grow;
                      dogs retain puppy coat and condition progresses to hair
                      loss over much of the body; thin skin, scales,
                      and secondary
                      infections | Special blood testing for
                      the presence of certain hormones | Hormone replacement therapy | 
                  
                    | Post-clipping alopecia | Hair may not grow back
                      immediately after it has been clipped; which animals may
                      be affected can not be predicted; more common in dogs with
                      thick undercoats e.g., Huskies and Chows | Continued lack of growth in
                      hair that was clipped, e.g., for surgery | History | None; hair will eventually
                      regrow, but may take up to 24 months | 
                  
                    | Pressure sores (decubital
                      ulcers) | Lesions occur over bony
                      prominences like elbows; common in larger recumbent dogs | Start as red, hairless areas
                      and progress to draining ulcers;
                      may become infected | Clinical signs, biopsy | Keep area clean and prevent
                      contact with urine; antibiotics; apply donut bandages,
                      which provide padding around but not over the ulcer;
                      surgical treatment is sometimes necessary; prevent ulcers
                      by turning the dog every 2 hours | 
                  
                    | Pyoderma-superficial (See Folliculitis) |  |  |  |  | 
                  
                    | Ringworm | Infection with several types of fungus | Hair loss, scaliness,
                      crusty
                      areas, pustules,
                      vesicles,
                      some itching; can develop a draining nodule
                      called a 'kerion' | Culture | Miconazole, lime sulfur dips; oral griseofulvin
                      or itraconazole | 
                  
                    | Sarcoptic
                      mange | Infection with the Sarcoptes mite | Intense itching and self-trauma, hair loss, papules,
                      crusts,
                      and scales | Skin scraping and microscopic examination - the mite is
                      often very difficult to find | Amitraz (Mitaban) dips (off-label use*); ivermectin
                      (off-label use*) | 
                  
                    | Schnauzer
                      comedo syndrome | Uncommon; only seen in
                      Miniature Schnauzers | Comedones (black heads) on
                      back, mild itching; may see secondary
                      infection, thinning of hair; small crusts may
                      develop | Clinical signs, breed, skin
                      biopsy | Long-term antiseborrheic
                      shampoos; sometimes antibiotics and retinoids | 
                  
                    | Sebaceous adenitis | Sebaceous
                      glands are destroyed, cause unknown; certain
                      breeds more susceptible | Short-haired breeds:
                      circular areas of hair loss with fine scale;
                      long-haired breeds: more widespread hair loss and scale,
                      hair mats easily; may see itching in all breeds | Clinical signs, breed, skin
                      biopsy | Antiseborrheic shampoos,
                      fatty acid supplements; in more severe cases, steroids,
                      retinoids | 
                  
                    | Seborrhea | Can be primary (inherited)
                      or secondary (resulting from other disease processes such
                      as allergies, hypothyroidism) | Scales; depending upon the
                      type, may have a dry or oily coat; odor; some scratching;
                      may see hair loss | Blood tests, skin scrapings,
                      etc., to find underlying cause | Treat underlying cause if
                      present; antiseborrheic shampoos; fatty acid supplements | 
                  
                    | Sertoli cell tumor | Tumor
                      of the testicles in middle-aged dogs | Male dogs take on female
                      sexual characteristics; hair loss, increased skin pigment,
                      reddened area on prepuce | Physical exam | Castration | 
                  
                    | Solar
                      dermatosis | Skin reaction to sunlight,
                      especially unpigmented skin; most common on the noses of
                      Collies, Shelties, and similar breeds | Redness, hair loss, and
                      scaling on nose and ears, later crusts
                      and ulcers | History, breed, physical
                      exam, skin biopsy | Must avoid further sun
                      exposure, especially 9 am - 3 pm; sunblock; steroids;
                      tattoo nose or apply black ink | 
                  
                    | Tail dock neuroma | Nerve regrowth after tail
                      docking causes symptoms | Nodule
                      at site of docking, itching with self-mutilation, hair
                      loss, and hyperpigmentation | History and symptoms | Surgical removal | 
                  
                    | Tail gland hyperplasia | Dogs have a sebaceous
                      gland on the top of the tail near its base; in
                      this disorder, the gland enlarges; seen in unneutered dogs
                      and secondary to other diseases such as hypothyroidism | Oily area, hair loss, crusts,
                      and hyperpigmentation
                      on area over gland | Clinical signs; look for
                      underlying cause | Castration may help; treat
                      underlying cause; surgical removal | 
                  
                    | Testosterone responsive
                      dermatosis (hypoandrogenism) | More common in old neutered
                      dogs, and in Afghans | Dull, scaly,
                      dry coat; seborrhea; hair loss in genital and anal areas
                      progressing onto trunk | Physical exam and history;
                      eliminate other causes; response to therapy | Testosterone replacement
                      therapy | 
                  
                    | Vitamin A responsive
                      dermatosis | May not be due to an actual
                      deficiency of Vitamin A, but does respond to increased
                      levels of Vitamin A in the diet; more common in Cocker
                      Spaniels | Seborrhea; odor; hair pulls
                      out easily; pads of feet thickened; thick scales
                      on chest and abdomen, especially around nipples | Clinical signs, breed, skin
                      biopsy | Lifetime treatment with
                      Vitamin A | 
                  
                    | Zinc responsive dermatosis | Three types: I in Huskies
                      and Malamutes; II in rapidly growing puppies of large
                      breeds; III in English Bull Terriers | Crusting
                      and scaling, redness, hair loss, sometimes oily skin,
                      secondary bacterial infections common | History, breed, physical
                      exam, skin biopsy | Correct any dietary
                      deficiency, medicated shampoos, treat secondary
                      infections |